Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.

نویسندگان

  • Yan Zhuang
  • Waithaka Mwangi
  • Wendy C Brown
  • William C Davis
  • Jayne C Hope
  • Guy H Palmer
چکیده

Immature dendritic cells (DCs) resident in bovine spleens represent a distinct CD11a(+) CD11c(+) CD13(+) CD172(+) CD205(+) population compared to those circulating in peripheral blood or trafficking via afferent lymph. Upon cytokine-induced maturation, splenic DCs both efficiently present antigen in the stimulation of allogeneic lymphocyte proliferation and recall antigen-specific responses.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 13 9  شماره 

صفحات  -

تاریخ انتشار 2006